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DIABETES is in essence a chronic caloric excess problem

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  • bic_cherry's Avatar
    440 posts since Jul '05
    • DIABETES is in essence a chronic caloric excess problem; marked by high glucose levels, insulin resistance caused by high visceral fat (fully saturated adipose cells) due to relatively insufficient activity (exercise) resulting in excessive caloric accumulation (visceral fat etc).

      (Just like traffic jams are harmful to Singapore).

      Both fat cells and muscle cells are instructed by hormone insulin to absorb glucose from blood. However, fat cells and undeveloped (atrophied+ fat saturated) muscle tissues have limited glucose absorption capability either due to fat saturation or else poor function (muscle volume lack due to lack of regular aerobic and weight bearing exercise) respectively.

      Marathon runners consume pure glucose during competitions as an instant energy source but all Olympic standard Marathon runners have minimal visceral fat (and ostensibly no insulin resistance) due to their high metabolism lifestyle in running long distance in training everyday.

      Due to the ready availability of high caloric food in Singapore and the encouragement to eat more ("cashless" payment options), Singaporeans need to exercise more to build more muscle volume and function to increase their calorie burning capacity vz increasing both their resting as well as maximum metabolic rate, as well as reduction of visceral fat so that glucose produced from food can be absorbed by muscles and unsaturated adipose (fat) cells.

      Singapore has done well to make our roads free from traffic jams by limiting the car population with limited COEs, scrapping cars with expired COEs so that roads are optimally used. Calories too can be controlled vz effective supply and demand adjustments: more non-digestible vegetable matter, complex foods: unprocessed natural fat and protein can lengthen the duration of digestion (satiety) and thus reduce between meal hunger pangs whilst increased exercise and measurable volumetric increase in muscle mass can increase baseline metabolic rate to allow unsaturated adipose cells to do their rightful job in responding to insulin and absorb glucose from blood.

      A high glucose level due to supply + demand imbalances is like a road jam-packed with cars causing road damage (excessive start-stop vehicle motions) and environmental damage due to air pollution due to excessive vehicle volume and travel duration).

      Diabetes is a disease of chronic caloric excess and sedentary life resulting in fully saturated adipose Cells and atrophied fat saturated muscle tissue: insensate to insulin due to physical limits in caloric storage being exceeded/ reached resulting in insulin resistance and consequent blood glucose excess which is self-destructive and in the long run, the cause of many diabetes related complications like blindness, cancer, kidney failure, impotence, heart failure, amputations, frequent infections and stroke (/dementia).

    • zhihau (SBY) wroteIt's not as simple as input vs output kind of thing. Here's an analogy.

      You pump petrol in a car and it drives the car engine, the car moves. Just as it's like our bodies, the food we eat fuels our activities. The car is made up of many small parts which are subjected to wear and tear and may break down. Our bodies are made up of many cells, each cell having many chemical pathways and influence surrounding cells by biochemical signaling. The downstream cascade may go haywire.

      The choice of petrol can be high octane or low octane, the car can still break down for some funny reasons, just as how we get diabetes despite our high calorie or low calorie diets. It's more of understanding the process of pancreas producing and secreting insulin and glucagon and how these processes help moderate blood glucose levels.

      Genetic disposition, stress levels, diseases can all have a hand in causing diabetes. Pinning the blame squarely on the diet is not correct and very irresponsible.

      Of course it is primarily a CALORIC input and output issue. Every fat(adipose) and muscle cell has a finite limit where caloric content is concerned and any further increase would mandate creation of more fat cells since muscle mass is unlikely to increase without strength training or aerobic exercise .

      Thus the resistance to insulin due to already energy saturated cells.

      With insufficient demand for energy expenditure due to sedentary lifestyles, the pancreas has no choice but to go into overdrive to lower blood glucose levels because high blood glucose is TOXIC to cells (inflammation of blood vessels is what causes heart attacks (atherosclerosis), blindness, kidney failure, amputation etc). High insulin levels can also promote cancer because insulin and human growth hormone have similar origins/function.

      Finally, the system breaks down, firstly due to high blood glucose causing damage to the pancreas itself amongst others, secondarily due to overworked pancreas, fatigued to the point of failure due to the insulin production overdrive.

      Thus, diabetes is indeed a disease caused by caloric consumption being in excess of caloric expenditure resulting in all the excess energy accumulation in the body causing damage everywhere inside (just like how u damage a lithium battery when u charge it to ABOVE capacity).

      For those economically inclined, diabetes is simply a failure of caloric economics with the excess calories causing havoc being too much to properly be absorbed by cells already at their maximum caloric storage limit.

  • Garystevens004's Avatar
    9 posts since Oct '17
    • I learned a lot from this topic. Great info. So we must be health cautios. Educate others about this kind of ailment.

  • FranC76's Avatar
    2 posts since Oct '17
    • Just my 2 cents' worth.. you should differentiate the different types of diabetes:

      Type 1 Diabetics: insulin deficiency from the pancreas cells, resulting in cells not being able to absorb the glucose in the blood stream, leading to higher than normal levels of blood sugar aka 'diabetes'. In Type 1 DM, calorie intake does not affect blood sugar levels because the body cannot produce enough insulin for cells to take in the glucose. Type 1 DM is sometimes also known as child-onset diabetes (because it usually occurs in children, and requires a lifetime injection of insulin to control blood sugar levels).

      Type 2 Diabetes: cell signaling regulation problem. In Type 2 diabetes, usually what happens in that the muscle and liver cells, become "resistant", or faulty to insulin, resulting in high blood glucose levels. In Type 2 DM, yes it is partly true that excess caloric intake is a contributing factor to the onset of diabetes. Type 2 diabetes is the most common type of blood sugar disorder in the world.

      Actually, there are other sub-sets of diabetes. For instance, Gestational diabetes (GDM), adult onset diabetes etc with different causes. Therefore, not all diabetes are due to excess caloric intake (though over eating does contribute to the risks of getting diabetes smile.png)

      Edited by FranC76 23 Oct `17, 3:57PM
  • Ronin63's Avatar
    8 posts since Dec '17
    • Face it, it seems like its seems too far a task for the average person to deny gluttony. Even if we're low on cash, we just plain don''t want to show moderation, its our nature to eat what we want, when we want, and how much we want. Our behavior will never change. 

  • PokemonGoGoGo's Avatar
    10 posts since Jan '18
  • Giorson Parsey's Avatar
    65 posts since Dec '17
    • Overview

      Diabetes mellitus refers to a group of diseases that affect how your body uses blood sugar (glucose). Glucose is vital to your health because it's an important source of energy for the cells that make up your muscles and tissues. It's also your brain's main source of fuel.


      If you have diabetes, no matter what type, it means you have too much glucose in your blood, although the causes may differ. Too much glucose can lead to serious health problems.

      Chronic diabetes conditions include type 1 diabetes and type 2 diabetes. Potentially reversible diabetes conditions include prediabetes — when your blood sugar levels are higher than normal, but not high enough to be classified as diabetes — and gestational diabetes, which occurs during pregnancy but may resolve after the baby is delivered.


      Diabetes symptoms vary depending on how much your blood sugar is elevated. Some people, especially those with prediabetes or type 2 diabetes, may not experience symptoms initially. In type 1 diabetes, symptoms tend to come on quickly and be more severe.

      Some of the signs and symptoms of type 1 and type 2 diabetes are:

      • Increased thirst
      • Frequent urination
      • Extreme hunger
      • Unexplained weight loss
      • Presence of ketones in the urine (ketones are a byproduct of the breakdown of muscle and fat that happens when there's not enough available insulin)
      • Fatigue
      • Irritability
      • Blurred vision
      • Slow-healing sores
      • Frequent infections, such as gums or skin infections and vaginal infections

      Although type 1 diabetes can develop at any age, it typically appears during childhood or adolescence. Type 2 diabetes, the more common type, can develop at any age, though it's more common in people older than 40.

      When to see a doctor

      • If you suspect you or your child may have diabetes. If you notice any possible diabetes symptoms, contact your doctor. The earlier the condition is diagnosed, the sooner treatment can begin.
      • If you've already been diagnosed with diabetes. After you receive your diagnosis, you'll need close medical follow-up until your blood sugar levels stabilize.


      To understand diabetes, first you must understand how glucose is normally processed in the body.

      How insulin works

      Insulin is a hormone that comes from a gland situated behind and below the stomach (pancreas).

      • The pancreas secretes insulin into the bloodstream.
      • The insulin circulates, enabling sugar to enter your cells.
      • Insulin lowers the amount of sugar in your bloodstream.
      • As your blood sugar level drops, so does the secretion of insulin from your pancreas.

      The role of glucose

      Glucose — a sugar — is a source of energy for the cells that make up muscles and other tissues.

      • Glucose comes from two major sources: food and your liver.
      • Sugar is absorbed into the bloodstream, where it enters cells with the help of insulin.
      • Your liver stores and makes glucose.
      • When your glucose levels are low, such as when you haven't eaten in a while, the liver breaks down stored glycogen into glucose to keep your glucose level within a normal range.

      Causes of type 1 diabetes

      The exact cause of type 1 diabetes is unknown. What is known is that your immune system — which normally fights harmful bacteria or viruses — attacks and destroys your insulin-producing cells in the pancreas. This leaves you with little or no insulin. Instead of being transported into your cells, sugar builds up in your bloodstream.

      Type 1 is thought to be caused by a combination of genetic susceptibility and environmental factors, though exactly what many of those factors are is still unclear.

      Causes of prediabetes and type 2 diabetes

      In prediabetes — which can lead to type 2 diabetes — and in type 2 diabetes, your cells become resistant to the action of insulin, and your pancreas is unable to make enough insulin to overcome this resistance. Instead of moving into your cells where it's needed for energy, sugar builds up in your bloodstream.

      Exactly why this happens is uncertain, although it's believed that genetic and environmental factors play a role in the development of type 2 diabetes. Being overweight is strongly linked to the development of type 2 diabetes, but not everyone with type 2 is overweight.

      Causes of gestational diabetes

      During pregnancy, the placenta produces hormones to sustain your pregnancy. These hormones make your cells more resistant to insulin.

      Normally, your pancreas responds by producing enough extra insulin to overcome this resistance. But sometimes your pancreas can't keep up. When this happens, too little glucose gets into your cells and too much stays in your blood, resulting in gestational diabetes.

      God bless giorson parsey... amen...

      Risk factors

      Risk factors for diabetes depend on the type of diabetes.

      Risk factors for type 1 diabetes

      Although the exact cause of type 1 diabetes is unknown, factors that may signal an increased risk include:

      • Family history.Your risk increases if a parent or sibling has type 1 diabetes.
      • Environmental factors. Circumstances such as exposure to a viral illness likely play some role in type 1 diabetes.
      • The presence of damaging immune system cells (autoantibodies). Sometimes family members of people with type 1 diabetes are tested for the presence of diabetes autoantibodies. If you have these autoantibodies, you have an increased risk of developing type 1 diabetes. But not everyone who has these autoantibodies develops diabetes.
      • Dietary factors. These include low vitamin D consumption, early exposure to cow's milk or cow's milk formula, and exposure to cereals before 4 months of age. None of these factors has been shown to directly cause type 1 diabetes.
      • Geography. Certain countries, such as Finland and Sweden, have higher rates of type 1 diabetes.

      Risk factors for prediabetes and type 2 diabetes

      Researchers don't fully understand why some people develop prediabetes and type 2 diabetes and others don't. It's clear that certain factors increase the risk, however, including:

      • Weight. The more fatty tissue you have, the more resistant your cells become to insulin.
      • Inactivity. The less active you are, the greater your risk. Physical activity helps you control your weight, uses up glucose as energy and makes your cells more sensitive to insulin.
      • Family history. Your risk increases if a parent or sibling has type 2 diabetes.
      • Race. Although it's unclear why, people of certain races — including blacks, Hispanics, American Indians and Asian-Americans — are at higher risk.
      • Age. Your risk increases as you get older. This may be because you tend to exercise less, lose muscle mass and gain weight as you age. But type 2 diabetes is also increasing dramatically among children, adolescents and younger adults.
      • Gestational diabetes. If you developed gestational diabetes when you were pregnant, your risk of developing prediabetes and type 2 diabetes later increases. If you gave birth to a baby weighing more than 9 pounds (4 kilograms), you're also at risk of type 2 diabetes.
      • Polycystic ovary syndrome. For women, having polycystic ovary syndrome — a common condition characterized by irregular menstrual periods, excess hair growth and obesity — increases the risk of diabetes.
      • High blood pressure. Having blood pressure over 140/90 millimeters of mercury (mm Hg) is linked to an increased risk of type 2 diabetes.
      • Abnormal cholesterol and triglyceride levels. If you have low levels of high-density lipoprotein (HDL), or "good," cholesterol, your risk of type 2 diabetes is higher. Triglycerides are another type of fat carried in the blood. People with high levels of triglycerides have an increased risk of type 2 diabetes. Your doctor can let you know what your cholesterol and triglyceride levels are.

      Risk factors for gestational diabetes

      Any pregnant woman can develop gestational diabetes, but some women are at greater risk than are others. Risk factors for gestational diabetes include:

      • Age. Women older than age 25 are at increased risk.
      • Family or personal history. Your risk increases if you have prediabetes — a precursor to type 2 diabetes — or if a close family member, such as a parent or sibling, has type 2 diabetes. You're also at greater risk if you had gestational diabetes during a previous pregnancy, if you delivered a very large baby or if you had an unexplained stillbirth.
      • Weight. Being overweight before pregnancy increases your risk.
      • Race. For reasons that aren't clear, women who are black, Hispanic, American Indian or Asian are more likely to develop gestational diabetes.


      Long-term complications of diabetes develop gradually. The longer you have diabetes — and the less controlled your blood sugar — the higher the risk of complications. Eventually, diabetes complications may be disabling or even life-threatening. Possible complications include:

      • Cardiovascular disease. Diabetes dramatically increases the risk of various cardiovascular problems, including coronary artery disease with chest pain (angina), heart attack, stroke and narrowing of arteries (atherosclerosis). If you have diabetes, you are more likely to have heart disease or stroke.
      • Nerve damage (neuropathy). Excess sugar can injure the walls of the tiny blood vessels (capillaries) that nourish your nerves, especially in your legs. This can cause tingling, numbness, burning or pain that usually begins at the tips of the toes or fingers and gradually spreads upward. Left untreated, you could lose all sense of feeling in the affected limbs. Damage to the nerves related to digestion can cause problems with nausea, vomiting, diarrhea or constipation. For men, it may lead to erectile dysfunction.
      • Kidney damage (nephropathy). The kidneys contain millions of tiny blood vessel clusters (glomeruli) that filter waste from your blood. Diabetes can damage this delicate filtering system. Severe damage can lead to kidney failure or irreversible end-stage kidney disease, which may require dialysis or a kidney transplant.
      • Eye damage (retinopathy). Diabetes can damage the blood vessels of the retina (diabetic retinopathy), potentially leading to blindness. Diabetes also increases the risk of other serious vision conditions, such as cataracts and glaucoma.
      • Foot damage. Nerve damage in the feet or poor blood flow to the feet increases the risk of various foot complications. Left untreated, cuts and blisters can develop serious infections, which often heal poorly. These infections may ultimately require toe, foot or leg amputation.
      • Skin conditions. Diabetes may leave you more susceptible to skin problems, including bacterial and fungal infections.
      • Hearing impairment. Hearing problems are more common in people with diabetes.
      • Alzheimer's disease. Type 2 diabetes may increase the risk of Alzheimer's disease. The poorer your blood sugar control, the greater the risk appears to be. Although there are theories as to how these disorders might be connected, none has yet been proved.

      Complications of gestational diabetes

      Most women who have gestational diabetes deliver healthy babies. However, untreated or uncontrolled blood sugar levels can cause problems for you and your baby.

      Complications in your baby can occur as a result of gestational diabetes, including:

      • Excess growth. Extra glucose can cross the placenta, which triggers your baby's pancreas to make extra insulin. This can cause your baby to grow too large (macrosomia). Very large babies are more likely to require a C-section birth.
      • Low blood sugar. Sometimes babies of mothers with gestational diabetes develop low blood sugar (hypoglycemia) shortly after birth because their own insulin production is high. Prompt feedings and sometimes an intravenous glucose solution can return the baby's blood sugar level to normal.
      • Type 2 diabetes later in life. Babies of mothers who have gestational diabetes have a higher risk of developing obesity and type 2 diabetes later in life.
      • Death. Untreated gestational diabetes can result in a baby's death either before or shortly after birth.

      Complications in the mother can also occur as a result of gestational diabetes, including:

      • Preeclampsia.This condition is characterized by high blood pressure, excess protein in the urine, and swelling in the legs and feet. Preeclampsia can lead to serious or even life-threatening complications for both mother and baby.
      • Subsequent gestational diabetes. Once you've had gestational diabetes in one pregnancy, you're more likely to have it again with the next pregnancy. You're also more likely to develop diabetes — typically type 2 diabetes — as you get older.

      Complications of prediabetes

      Prediabetes may develop into type 2 diabetes.


      Type 1 diabetes can't be prevented. However, the same healthy lifestyle choices that help treat prediabetes, type 2 diabetes and gestational diabetes can also help prevent them:

      • Eat healthy foods. Choose foods lower in fat and calories and higher in fiber. Focus on fruits, vegetables and whole grains. Strive for variety to prevent boredom.
      • Get more physical activity. Aim for 30 minutes of moderate physical activity a day. Take a brisk daily walk. Ride your bike. Swim laps. If you can't fit in a long workout, break it up into smaller sessions spread throughout the day.
      • Lose excess pounds. If you're overweight, losing even 7 percent of your body weight — for example, 14 pounds (6.4 kilograms) if you weigh 200 pounds (90.9 kilograms) — can reduce the risk of diabetes. To keep your weight in a healthy range, focus on permanent changes to your eating and exercise habits. Motivate yourself by remembering the benefits of losing weight, such as a healthier heart, more energy and improved self-esteem.

      Sometimes medication is an option as well. Oral diabetes drugs such as metformin (Glucophage, Glumetza, others) may reduce the risk of type 2 diabetes — but healthy lifestyle choices remain essential.

      Have your blood sugar checked at least once a year to check that you haven't developed type 2 diabetes.

      Edited by Giorson Parsey 25 Feb `18, 6:35PM
  • Aceofaceent's Avatar
    69 posts since Apr '18
    • It can be due to the poisoned liver that cannot process the insulin. The liver can be gradually be poisoned by the wrong food intake, medicine or the inhalation of the poor quality air triggered by the burning of the forests, fuel, cigarettes, gas, coal, charcoals, incense and other toxic pollutants . Alternatively, could be due to spraying the insecticides, pesticides, hair products, perfumes, air fresheners or fogging.

      The liver can be poisoned by drinking the carbonated drinks or sugary fluids or eating deep fried, stir fried or pan fried food.

      Once the poisoned organs can’t perform their normal functions chronic, terminal or autoimmune diseases will result.

      Whatever you eat, drink or inhale dictates the state of a person’s health.

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