United have been drawn away to Crewe Alexandra in the Carling Cup third round.
It'll be the sixth meeting between the two sides, the most recent of which took place just under two years ago when the pair were drawn together at exactly the same stage of the competition.
Goals from Alan Smith and Liam Miller, plus an own goal from Stephen Foster gave the Reds a 3-0 victory at The Alexandra Stadium.
This year's tie will be played the week commencing 23 October.
United are unbeaten against Crewe in the five meetings between the two sides, although four of those games took place in the late 1800's!
Meanwhile, Chelsea face a tricky trip to Blackburn, while Arsenal will travel to West Brom. Liverpool play host Reading and Newcastle will entertain fellow Premiership team Portsmouth at St. James' Park.
Carling Cup 3rd Round Draw
Wycombe v Doncaster
Sheffield United v Birmingham
Leicester v Aston Villa
Watford v Hull
Leeds v Southend
Chesterfield v West Ham
Notts County v Southampton
Newcastle v Portsmouth
Charlton v Bolton
Liverpool v Reading
West Brom v Arsenal
Port Vale v Norwich
Everton v Luton
MK Dons v Tottenham
Crewe v Manchester United
Blackburn v Chelsea
Ties to be played W/C 23 October.