Dirk Kuyt and Daniel Agger were both injured on international duty on Tuesday night, giving Liverpool boss Roy Hodgson more to worry about ahead of the Merseyside derby on Sunday.
Kuyt's injury could be the more serious as he lasted only 29 minutes of Holland's game against Sweden before leaving with what appeared to be a bad ankle injury.
Agger, making his comeback from a groin problem, lasted only 39 minutes of Denmark's game against Cyprus.
According to the Liverpool website, both players will be assessed on their return to Melwood before any decision is made about the weekend.