Very horrifying pictures
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Harlequin type ichthyosis (also harlequin ichthyosis, ichthyosis congenita, or keratosis diffusa fetalis), the most severe form of congenital ichthyosis, is characterized by a thickening of the keratin layer in fetal human skin, appearing as massive, diamond-shaped scales. In addition, the eyes, ears, mouth, and other appendages may be abnormally contracted. The scaly keratin limits the child's movement, and because it is cracked where normal skin would fold, it is easily pregnable by bacteria and other contaminants, resulting in a serious risk of fatal infection.
Sufferers are known as harlequin fetuses, harlequin babies, or harlequins.
The harlequin type designation comes from both the baby's apparent facial expression and the diamond-shape of the scales (resembling the costume of Arlecchino), which are caused by severe hyperkeratosis. Seventeenth century entertainers known as jesters, or harlequins, wore costumes with diamond patterns on them, as well as a particular style of face paint. The features of the harlequin fetus resemble this stylized makeup, and their faces are often pulled tight into grim parodies of a clown's smile. The disease can be diagnosed in the womb by way of fetal skin biopsy.
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views # so high
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i was right...its indeed a genetic mutation
wiki:
Mutations in the ABCA12 gene cause harlequin ichthyosis. The ABCA12 gene makes a protein that is essential for the normal development of skin cells. Although the protein's exact function is unknown, researchers believe that it probably plays a major role in the transport of lipids (fats) in the outermost layer of skin (the epidermis). Mutations in the ABCA12 gene lead to the production of an abnormally small version of the protein that cannot transport lipids properly. The loss of functional ABCA12 protein disrupts the normal development of the epidermis, preventing the skin from forming an effective barrier and resulting in the hard, thick scales characteristic of harlequin ichthyosis.
This condition is likely inherited in an autosomal recessive pattern, which means two copies of the gene in each cell are altered. Most often, the parents of an individual with an autosomal recessive disorder are carriers of one copy of the altered gene but do not show signs and symptoms of the disorder. -
This birth disorder isn't something new. I've seen other pictures of those affected babies on other forums. Do a Google or Yahoo search on it. The deep spaces on the skin are actually cracks. But still, i'm getting goosebumps just by typing this...
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dudes why are we even discussing this?Originally posted by Lim Wei Ming:This birth disorder isn't something new. I've seen other pictures of those affected babies on other forums. Do a Google or Yahoo search on it. The deep spaces on the skin are actually cracks. But still, i'm getting goosebumps just by typing this...
while i do feel for the babies and the parents of said babies there is a time and a place for those kind of pictures sadly you picked a bad place for them
why post such graphic photos here?
where anyone could find them (even little children younger than me )
FYI: if you are gonna send pictures though post a hyperlink then we can get a choice where or not we see them...
I for one did not want to see such graphic pictures before dinner... now i am turned off my food for the rest of the evening..
thank you
Simsy -
What can modern medicine do for these unfortunate children? What's their life expectancy? Their chances of leading normal lives?
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genetics, they alter the genes of the embryo by cutting up certain dna strands and implanting it from other animals.
If its unsucessful, then i really had no idea how did tis happen. Could be premature birth, or diseases -
WTF> This is another sick thread....
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sorry i didnt know u get turned off by such pictures...actually these pictures are very fascinating to me i dont get turned off at all i dont think they're sick, just unfortunate..they're just humans with different physical appearances, u dont have to insult them and call em sick or whatever rude words there are to describe them.
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OMg thats damn sad man... a slaute to the babies...
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why glorifiy it then Ashiene... they have suffered enough without people making fun of those pictures which are very graphic to begin with?Originally posted by Ashiene:sorry i didnt know u get turned off by such pictures...actually these pictures are very fascinating to me i dont get turned off at all i dont think they're sick, just unfortunate..they're just humans with different physical appearances, u dont have to insult them and call em sick or whatever rude words there are to describe them.
I was more taking issue with the fact that i am sure there are children underage on these forums.. and as such i was considering maybe that was too graphic for there age group to understand....
it takes a lot for me to be put off by things generally at the best of times but those pictures ashiene did turn me off...
Simsy -
Not all the images were those of congenital icthyosis. The last picture from the first set of images looks like holoprosencephaly with a proboscis.
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eh i wonder why reno not interested in studying em
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HOLY S@IT
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OMG, this is so SADDENING.
And I feel like vomitting.
I mean, face it. This world is filled with imperfections. But to this extend..?!?! God is so unfair. No offence. I mean, ok. He is fair.
Situation #1.
Helen Keller was blind and deaf. (Right?) BUT she had her other senses to find out WHAT was in front of her, what was happening and so on.
Situation #2.
This one is about the one here. The mutated baby or something. Forgot already. But is she/he able to live? Is she/he able to DO something? No! They DIE before the age of 5. As I research.
Man, this images are making me SICK. I sure to get nightmares....
Sometimes, life is like this. We just have to accept it. -
some of the wounds and other mutations i think are due to infections and other causes due to the skin problems.. they don't die from those cracks but to the infections that afflicted them due to those cracks. sorta like aids..? treatment is better than before, if i remember right, one such case was featured on the news some years ago. the person grew past teenage.. correct is wrong.
ps: im eating chicken wings in the meantime.