Neotame has a similar structure to aspartame, the chemicals used in its manufacturing process seem to make the sweetener even more toxic than aspartame.
Both aspartame and Neotame are made up of substances which metabolize into a highly toxic poison known as formaldehyde. In addition, they contain an exctiotoxic amino acid that agitates, thereby damaging nerves. Although very similar to aspartame in chemical structure, Neotame has one chemical added that aspartame does not possess – 3-dimethylbutyl, which just so happens to be on the Environmental Protection Agency’s most hazardous chemical list.