Nicotine activates enzyme aiding cancer

• www

  4 Jan 03, 12:38

  Nicotine activates enzyme aiding cancer
  
  
  
  WASHINGTON - Nicotine makes smoking addictive and is bad for the heart, but 60 other cigarette chemicals are blamed for causing cancer. Now, some biochemists say nicotine might help set the stage for those chemicals to do their dirty work.
  
  Certain tobacco chemicals trigger cellular genetic damage. Damaged cells are supposed to 'commit suicide'; if they do not, the damage accumulates enough to turn cancerous.
  
  Nicotine activates an enzyme reaction which inhibits cellular suicide, says new research by scientists at the National Cancer Institute.
  
  Nicotine starts activating that enzyme, called Akt, within minutes, while cancer-causing genetic damage takes hours to begin, institute researchers report in the latest Journal of Clinical Investigation. That suggests nicotine, along with other chemicals which block cell suicide, may make cells more vulnerable to the cancer-causers.
  
  'Nicotine is not a carcinogen; we're not trying to make that argument,' said study leader Phillip Dennis. But 'it may have a permissive effect' on cancer formation.
  
  Scientists first discovered nicotine may block cell suicide 10 years ago, said nicotine expert Neal Benowitz of the University of California, San Francisco. But the new research uncovers the actual enzyme involved.
  
  The question now is whether the effect matters to smokers using nicotine gum or patches in a bid to quit.
  
  'It's clearly better for people to stop smoking and use a patch than to continue smoking,' Dr Dennis said, adding that the study reinforces that anti-smoking medicines are for short-term use only.
  
  But Dr Benowitz said the study had used cells in laboratory dishes, while previous studies of snuff users - who do not absorb as many carcinogens as smokers - suggest there is little cancer risk from nicotine. --AP
  
  Cells more vulnerable
  
  Scientists at the National Cancer Institute say nicotine is not a carcinogen. But it may pave the way for cancer formation.
  
  It kick-starts an enzyme, called Akt, which inhibits suicide in damaged cells. This means nicotine may make cells more vulnerable to cancer-causing chemicals.
  
  morale of the story? dont smoke! smoking causes cancer!
• Si|verGer

  4 Jan 03, 15:49

  action speaks louder than words
  
  yawnzzzzzzzzzzzzzzzzzzzzzzzzzzzz
• startrightnow

  4 Jan 03, 15:51

  
• jOhO

  4 Jan 03, 16:43

  u suck!
• Si|verGer

  4 Jan 03, 16:44

  Originally posted by jOhO:

  u suck!

  does he? but isn't dat attract u to him?
• Storm

  4 Jan 03, 17:37

  Originally posted by jOhO:

  u suck!

  you tried him b4?
• Si|verGer

  4 Jan 03, 17:56

  Originally posted by Storm:

  you tried him b4?

  hahahaha dat a gd 1!!!
• Storm

  4 Jan 03, 18:22

  2 words:
  
  DON'T SMOKE!
  
  save money, save your lungs
• Si|verGer

  4 Jan 03, 19:22

  Originally posted by Storm:

  2 words:
  
  DON'T SMOKE!
  
  save money, save your lungs

  save $ buy more diamonds 4 her!
• jOhO

  4 Jan 03, 19:25

  Originally posted by Si|verGer:

  does he? but isn't dat attract u to him?

  yeah he does.. does it well too!
• jOhO

  4 Jan 03, 19:26

  Originally posted by Storm:

  you tried him b4?

  u too... u forgot??
• Parka

  4 Jan 03, 19:28

  Originally posted by Storm:

  2 words:
  
  DON'T SMOKE!
  
  save money, save your lungs

  You guys know which one is easier to get? Hit 4D or hit Cancer?
• whiteillum

  4 Jan 03, 19:33

  Originally posted by Si|verGer:

  save $ buy more diamonds 4 her!

  do not be conned gentlemen.....
  this here is a veri veri dangerous campaigneer for the "Men must buy diamonds for Women" Organisation.
  BEWARE!!
• Si|verGer

  4 Jan 03, 19:44

  Originally posted by jOhO:

  yeah he does.. does it well too!

  or u juz aiming his back?
• Si|verGer

  4 Jan 03, 19:45

  Originally posted by whiteillum:

  do not be conned gentlemen.....
  this here is a veri veri dangerous campaigneer for the "Men must buy diamonds for Women" Organisation.
  BEWARE!!

  diamonds r gers best frenxs!
• whiteillum

  4 Jan 03, 20:34

  Originally posted by Si|verGer:

  diamonds r gers best frenxs!

  so we are told
• Si|verGer

  4 Jan 03, 20:35

  Originally posted by whiteillum:

  so we are told

  eh tin diamonds & rose r the door to open a ger heart?
• whiteillum

  4 Jan 03, 20:41

  Originally posted by Si|verGer:

  eh tin diamonds & rose r the door to open a ger heart?

  haha
  i prefer sincerity and love
  
• Si|verGer

  4 Jan 03, 20:55

  Originally posted by whiteillum:

  haha
  i prefer sincerity and love
  

  of coz nutin beat sincerity, honesty, & true luv
• whiteillum

  4 Jan 03, 20:59

  Originally posted by Si|verGer:

  of coz nutin beat sincerity, honesty, & true luv

  of course
  did u realize we are replying to each other on 2 diff threads?
• Si|verGer

  4 Jan 03, 22:20

  Originally posted by whiteillum:

  of course
  did u realize we are replying to each other on 2 diff threads?

  yaya i did notice & i notice u seldom post! hw abt a intro 1st?
• whiteillum

  4 Jan 03, 22:24

  Originally posted by Si|verGer:

  yaya i did notice & i notice u seldom post! hw abt a intro 1st?

  yah sure
  22 male ch undergrad/trainee teacher
  u?
• Si|verGer

  5 Jan 03, 02:19

  Originally posted by whiteillum:

  yah sure
  22 male ch undergrad/trainee teacher
  u?

  oic i tot u r a ger! =X
  oops erm mi 18/f (19 tis yr)
  erm wer u teaching?
• whiteillum

  5 Jan 03, 09:58

  Originally posted by Si|verGer:

  oic i tot u r a ger! =X
  oops erm mi 18/f (19 tis yr)
  erm wer u teaching?

  not yet teaching i am afraid
  still doing my degree
  but i am training to be a pri sch teacher
• Estee

  5 Jan 03, 10:04

  hui si jiu shi hui si, chi bing qi ling dou hui ye si..............